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Sarcoidosis with Atypical Rounded Nodules

Sarcoidosis with Atypical Rounded Nodules▶ Watch on YouTube — age-restricted, cannot embed here

Imaging findings

Well-defined, rounded nodules with a lymphatic or perilymphatic distribution, clumping together, primarily in the mid-lungs on both radiograph and CT. Associated mediastinal lymphadenopathy was also present. While the nodules were unusually rounded (often more irregular or stellate in typical sarcoidosis), the overall distribution and lymphadenopathy were classic for the disease.

Key takeaways

Sarcoidosis characteristically presents with perilymphatic nodules and mediastinal lymphadenopathy. Although sarcoid nodules are often described as irregular or stellate, they can occasionally demonstrate a surprisingly rounded morphology. Recognizing the classic distribution and the presence of associated lymphadenopathy remains key to the diagnosis, even when nodule morphology is atypical.

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