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Sarcoidosis (Pulmonary and Hepatic Involvement)

Sarcoidosis (Pulmonary and Hepatic Involvement)▶ Watch on YouTube — age-restricted, cannot embed here

Imaging findings

Comparison chest radiographs show new diffuse reticular opacities (fine to medium) in the later study. CT confirms these are diffuse and affect all lobes, with a prominent perifissural distribution of small nodules intimately associated with the interlobar fissures.

Key takeaways

This case demonstrates pulmonary sarcoidosis presenting with a classic perifissural and diffuse reticulonodular pattern on CT. The patient had a prior liver biopsy in 2012 initially read as autoimmune hepatitis, but on re-review was re-diagnosed as granulomatous hepatitis, indicating multi-organ involvement (liver and lungs). Bradycardia also raised suspicion for cardiac sarcoidosis, highlighting the systemic nature of the disease.

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