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Pulmonary Cysts Associated with Chronic Lymphocytic Leukemia

Imaging findings

In a patient with a long-standing history of B-cell chronic lymphocytic leukemia dating back to 2006, CT shows a few pulmonary cysts, including one larger cyst with septations and residual internal tissue, along with several smaller cysts scattered in the lungs.

Key takeaways

These cysts are believed to represent a form of cystic lung disease associated with the underlying B-cell lymphoproliferative disorder, potentially related to lymphocytic infiltration and protein deposition obstructing small airways, an unusual but recognized pulmonary manifestation of CLL and related B-cell lymphoproliferative disorders.

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