CTICasesTracheobronchial Papillomatosis Associated with HPV-Positive Squamous Cell Carcinoma
Imaging findings
A patient in his 20s status post lobectomy for an HPV-positive squamous cell carcinoma of the right upper lobe has CT showing multiple small, stalactite-like polypoid nodules hanging into the tracheal lumen, without other pulmonary parenchymal nodules or cavities to suggest more diffuse airway papillomatosis.
Key takeaways
HPV-positive squamous cell lung cancer in a young patient can be accompanied by tracheal papillomatosis from the same viral infection, manifesting as small polypoid excrescences within the tracheal lumen; despite the tracheal involvement, this patient had no evidence of the diffuse pulmonary nodules or cavitary lesions that can occur with more extensive pulmonary papillomatosis.
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