Angioinvasive Cunninghamella (Mucormycosis) infection
Imaging findings
CT scan of a neutropenic patient shows multiple nodular opacities, including a dominant mass showing a reverse halo sign and an occluded feeding pulmonary artery branch. Lavage grew Cunninghamella.
Key takeaways
Cunninghamella is a genus within the Mucorales order. Angioinvasive mucormycosis classically presents with the reverse halo sign and arterial occlusion, representing hemorrhagic infarction, and is highly lethal in neutropenic patients.
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