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Aortic valve thrombus causing myocardial infarction in protein S deficiency

Imaging findings

CT and cardiac MRI demonstrate chronic PE (pulmonary artery webs), a thrombus on the aortic valve in the right coronary sinus of Valsalva causing RCA obstruction, and a corresponding inferior wall myocardial infarction.

Key takeaways

Protein S deficiency is a hypercoagulable state that predisposes to both venous and arterial thromboembolism. Thrombi on the aortic valve can embolize or directly obstruct the coronary ostia, causing acute myocardial infarction in young patients.

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