CTICasesPulmonary hamartoma
Imaging findings
Serial CT scans over 18 months show a slowly growing, slightly lobulated solitary pulmonary nodule in the setting of severe emphysema. FDG-PET scan demonstrates no uptake in the nodule, suggesting a benign etiology such as a hamartoma.
Key takeaways
Benign lesions such as pulmonary hamartomas can demonstrate progressive growth over time, mimicking malignancy. In patients with severe emphysema who are poor candidates for biopsy or resection, a negative FDG-PET scan carries significant weight in predicting a benign etiology, allowing for conservative management.
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