CTICasesExcipient lung disease (talc granulomatosis) in cystic fibrosis
Imaging findings
CT scan of a cystic fibrosis patient shows progressive RV dilation and septal flattening (pulmonary hypertension) associated with the development of tiny centrilobular nodules. Cytology and clinical history confirmed IV injection of crushed oxycodone tablets.
Key takeaways
Intravenous injection of crushed oral tablets (such as oxycodone) leads to embolization of insoluble excipients (like talc or microcrystalline cellulose) into the pulmonary capillaries, causing talc granulomatosis and severe pulmonary hypertension.
AI-assisted summary — may contain errors. Verify against the source video. Learn more
More from this webinar
- Mucinous adenocarcinoma arising in type 1 CPAMCongenital
- Legionella pneumonia simulating EVALIInfection
- Mediastinitis and tracheoesophageal fistula from malpositioned chemotherapy port catheterIatrogenic
- Thoracic lymphangiomatosis presenting as chylothoraxVascular
- EVALI complicated by pneumothorax and subpleural cystExposure
- Inhalational talcosis presenting as hypersensitivity pneumonitisExposure
- Spontaneous coronary artery dissection (SCAD) Type 2Vascular
- Cystic tumor of the AV node and splenosisCongenital
See all cases from November 8, 2019 →
Related Exposure cases
- Excipient lung disease (talc granulomatosis)
- Excipient lung disease secondary to oral painkiller abuse
- EVALI presenting as diffuse bronchocentric ground-glass nodules
- EVALI presenting as upper-lobe predominant ground-glass opacities
- EVALI mimicking radiation pneumonitis in a melanoma patient
- Vaping-associated desquamative interstitial pneumonia (DIP)