Chronic Progressive Pulmonary Blastomycosis with Cavitary Disease and Bronchiectasis
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Imaging findings
Initial radiographs and CT from 2012 show mass-like consolidation, significant volume loss in the upper lobes, emphysema, and dilated airways predominantly in the upper lobes. Follow-up radiographs and CT two years later demonstrate dramatic progression with severe bronchiectasis, extensive cavitary disease, spread of disease to the lower lobes, and fluid-filled cavities.
Key takeaways
Blastomycosis can present as a chronic, progressive lung infection leading to severe tissue destruction, cavitary disease, and bronchiectasis if left untreated, mimicking tuberculosis. Untreated cases, even initially mild-to-moderate, can evolve dramatically and may require aggressive therapy like amphotericin.
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