CTICasesMediastinal malignant peripheral nerve sheath tumor
Imaging findings
Chest CT and spinal MRI show a large, aggressive, heterogeneous mediastinal mass in a patient with neurofibromatosis, demonstrating direct extension into the adjacent spinal canal.
Key takeaways
Malignant peripheral nerve sheath tumors are aggressive sarcomas that often arise in patients with neurofibromatosis. In the posterior mediastinum, they can show bone erosion and intraspinal extension, presenting with chest pain or neurological symptoms.
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