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Cystic metastases of pleomorphic liposarcoma

Imaging findings

Serial chest CT scans demonstrate rapidly growing, bilateral pulmonary metastases, some of which present as thin-walled cystic lesions containing air-fluid levels or fluid-filled cavities of water attenuation, associated with a secondary spontaneous pneumothorax.

Key takeaways

Sarcomas, such as pleomorphic liposarcoma, are well-known to cause cystic and cavitary pulmonary metastases. These subpleural lesions are prone to rupture, leading to pneumothorax, and can mimic benign lung cysts on initial imaging.

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