CTICasesPulmonary Langerhans Cell Histiocytosis
Imaging findings
Chest CT of a female smoker shows diffuse, upper/mid-lung predominant, thick-walled pulmonary cysts and nodules. VEGF testing was negative, and clinical findings were consistent with PLCH.
Key takeaways
PLCH is strongly associated with tobacco smoking. It manifests as upper/mid-zone predominant thick-walled cysts and nodular lesions. Negative VEGF levels help exclude LAM in young female patients.
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