CTICasesSplenic Calcifications in Systemic Lupus Erythematosus
Imaging findings
Chest radiograph and CT show multiple dense, diffuse calcifications throughout the spleen in a patient with systemic lupus erythematosus (SLE) and renal failure.
Key takeaways
Diffuse splenic calcifications can occur in SLE (and renal failure). They must be distinguished from calcifications due to sickle cell disease (which typically show splenic atrophy) or prior granulomatous infections.
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