CTICasesAtypical Pulmonary Langerhans Cell Histiocytosis
Imaging findings
Chest CT in a 30-year-old female smoker of marijuana and tobacco shows diffuse, thick-walled pulmonary cysts with atypical basal predominance, complicated by bilateral pneumothoraces. Biopsy confirmed Langerhans cell histiocytosis (PLCH).
Key takeaways
PLCH typically spares the lung bases. However, atypical presentations with basal predominance can occur and can be complicated by recurrent, bilateral pneumothoraces, requiring differentiation from lymphangioleiomyomatosis (LAM).
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