CTICasesBronchiolitis obliterans syndrome (BOS) post-stem cell transplant
Imaging findings
Expiratory CT scan shows extensive, geographic mosaic attenuation with severe, bilateral air trapping (spared lucent lobules with attenuated vessels) in a patient post-HSCT for leukemia.
Key takeaways
BOS is a manifestation of pulmonary GVHD post-stem cell transplantation. On CT, it presents with severe constrictive bronchiolitis, characterized by extensive air trapping on expiratory imaging and mosaic perfusion.
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