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Marijuana-Associated Aspergillus Bronchitis

Imaging findings

In a woman with a heavy cigarette and daily marijuana smoking history, CT shows larger pulmonary nodules with an airways-centered, bronchocentric distribution that is upper-lobe predominant with some lower-lobe involvement, distinctly less peripheral than the pattern seen with septic emboli.

Key takeaways

An airway-centered, upper-lobe-predominant nodular pattern in a heavy marijuana smoker who grew Aspergillus on bronchoalveolar lavage reflects marijuana-associated Aspergillus bronchitis, since marijuana smoke is a recognized vector for Aspergillus contamination and inhalation directly into the central airways.

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