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LVAD Driveline Infection Extending to the Outflow Cannula

Imaging findings

In a second LVAD patient with progressive outflow cannula narrowing on serial CTs, the most recent study additionally shows new soft-tissue attenuation tracking along the outflow cannula into the anterior mediastinum, corresponding clinically to pus draining along the driveline exit site and Klebsiella bacteremia.

Key takeaways

New perigraft soft-tissue infiltration extending from an infected driveline into the mediastinum, in addition to outflow cannula narrowing, indicates that the cannula compromise here is infectious rather than the benign extraluminal fluid seen in an isolated, non-infected case -- distinguishing infected from sterile perigraft fluid collections in LVAD patients has direct management implications.

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