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Pulmonary Cryptococcosis

Imaging findings

Chest radiograph and CT in a 19-year-old woman demonstrate an irregular pulmonary nodule in the left lung apex surrounded by a small zone of consolidation. Serial imaging shows gradual consolidation of the primary apex lesion while surrounding satellite opacities resolve. Mild mediastinal lymphadenopathy is also present.

Key takeaways

Pulmonary cryptococcosis is an opportunistic fungal infection caused by Cryptococcus neoformans or Cryptococcus gattii. It typically presents on CT as single or multiple nodules, which may cavitate, or focal areas of consolidation, particularly in the upper lobes. It can occur in immunocompetent individuals but is more common and prone to dissemination in patients with underlying immune deficits.

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