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Diffuse Pulmonary Meningotheliomatosis

Imaging findings

Chest CT demonstrates numerous tiny, subcentimeter, bilateral pulmonary nodules in a random distribution. The nodules have remained stable over multiple years of serial CT imaging, initially suspected of representing metastases in a patient with history of lung cancer. Histopathologic analysis confirms minute pulmonary meningothelial-like nodules.

Key takeaways

Diffuse pulmonary meningotheliomatosis is a benign condition characterized by the proliferation of minute meningothelial-like nodules in the lung parenchyma. These nodules are usually incidental, microscopic findings, but when abundant, they can manifest as diffuse tiny nodules on CT, mimicking miliary infection or hematogenous metastases. They are typically stable and have a benign clinical course.

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