CTICasesEctopic Anterior Mediastinal Parathyroid Adenoma
Imaging findings
Sestamibi scintigraphy and SPECT/CT demonstrate physiologic uptake in the submandibular glands and thyroid, along with a distinct, hyperfunctioning focus of sestamibi activity in the anterior mediastinum. Contrast-enhanced CT correlation reveals a corresponding small, hypervascular nodule located along the anterior pericardial surface.
Key takeaways
Ectopic parathyroid tissue can be located anywhere along the path of thymic descent, from the neck down to the anterior mediastinum or pericardial surface. In patients with hyperparathyroidism and negative neck imaging, sestamibi SPECT/CT is highly valuable for localizing these ectopic adenomas to guide targeted surgical resection.
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