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Sarcoidosis with Galaxy Sign

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Imaging findings

Chest radiograph shows bilateral hilar and mediastinal lymphadenopathy, accompanied by ill-defined nodules in both lungs. CT scan of the chest demonstrates extensive parenchymal consolidation-like masses formed by the conglomeration of numerous small, distinct, interstitial nodules. These large, dense opacities exhibit a nodular periphery, creating the classic "sarcoid galaxy" sign.

Key takeaways

The sarcoid galaxy sign represents a mass-like conglomeration of small interstitial granulomas, which typically has a nodular border and surrounding satellite nodules. Sarcoidosis can present with neurological symptoms such as cranial nerve palsy, making chest imaging and biopsy of hilar lymph nodes essential for confirming non-necrotizing granulomas and establishing the systemic diagnosis.

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