CTICasesMediastinal Non-Seminomatous Germ Cell Tumor
Imaging findings
CT chest shows a massive, heterogeneous anterior mediastinal mass invading the superior vena cava and extending into the right atrium. PET-CT shows high FDG avidity, and serum tumor markers (AFP, beta-hCG) were elevated, confirming a non-seminomatous germ cell tumor (NSGCT).
Key takeaways
Primary mediastinal NSGCTs are aggressive tumors seen in young males. They frequently invade adjacent venous structures (SVC, right atrium) and are highly chemo-sensitive, though residual cystic or teratomatous components often require post-chemotherapy surgical resection.
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