CTICasesExtraosseous Multiple Myeloma
Imaging findings
CT chest shows multiple, large, soft tissue masses tracking extensively along the pleural spaces and mediastinum without the typical expansile rib lesions or skeletal lytic defects.
Key takeaways
Extramedullary or extraosseous plasmacytomas are a manifestation of advanced multiple myeloma. They typically present as soft tissue masses in the upper respiratory tract or pleura, and can simulate primary pleural malignancies (mesothelioma) or lymphoma, requiring biopsy to confirm plasma cell origin.
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