CTICasesLight Chain Deposition Disease Cysts
Imaging findings
Chest CT in a 44-year-old female shows diffuse, heterogeneous, clustered perivascular pulmonary cysts and ground-glass opacities, with negative serum VEGF levels. Biopsy confirmed light chain deposition disease.
Key takeaways
Light chain deposition disease can manifest as diffuse, irregular, perivascular lung cysts. A negative VEGF level helps differentiate this from lymphangioleiomyomatosis (LAM) in females of reproductive age.
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