CTICasesAvelumab-Induced Organizing Pneumonia
Imaging findings
Chest CT shows bilateral, basal-predominant consolidations with a perilobular and reversed halo (atoll) pattern in a patient receiving immunotherapy (avelumab) for abdominal liposarcoma. The pattern resolved spontaneously over one month.
Key takeaways
Drug-induced organizing pneumonia is a known immune-related adverse event of PD-1/PD-L1 inhibitors like avelumab. It can present with characteristic perilobular or reversed halo signs and may regress spontaneously or require corticosteroids.
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