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Subacute Scrofula (Tuberculosis)

Imaging findings

A non-contrast CT of the neck and chest demonstrates multiple enlarged cervical and supraclavicular lymph nodes, with a large, confluent nodal mass extending into the upper anterior mediastinum. Faint calcification is visible within the mediastinal and hilar lymph nodes, mimicking the pattern of sarcoidosis.

Key takeaways

Subacute scrofula (mycobacterial lymphadenitis) typically presents with bulky, asymmetric cervical and supraclavicular lymphadenopathy that can extend into the mediastinum. While calcified nodes can mimic sarcoidosis, the presence of systemic symptoms, regional asymmetric cervical involvement, and specific demographic risk factors should prompt biopsy to confirm tuberculosis.

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