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Pulmonary Toxoplasmosis (Diffuse Pneumonia) in a Stem Cell Transplant Recipient

Pulmonary Toxoplasmosis (Diffuse Pneumonia) in a Stem Cell Transplant Recipient▶ Watch on YouTube — age-restricted, cannot embed here

Imaging findings

A chest radiograph showed diffuse lung disease. CT images revealed ground-glass opacities with a peribronchial distribution, resembling pneumonia. Notably, there was a significant basal component, which deviates from typical viral pneumonia patterns.

Key takeaways

Pulmonary toxoplasmosis should be included in the differential diagnosis of diffuse lung disease in immunocompromised patients, particularly stem cell transplant recipients. The imaging pattern, while diffuse and resembling other pneumonias (e.g., viral or Pneumocystis), can have distinguishing features such as a prominent basal component. Lavage confirmed the diagnosis of toxoplasmosis, highlighting the importance of considering less common infections in this vulnerable population.

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