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Squamous Cell Carcinoma Invading the Left Atrium

Imaging findings

CT and PET-CT show a large squamous cell lung carcinoma in the left lung invading through the left inferior pulmonary vein into the body of the left atrium, presenting as an avid filling defect.

Key takeaways

Primary lung cancers can invade pulmonary veins and grow directly into the left atrium, mimicking a left atrial myxoma or thrombus. Contrast CT and PET-CT are useful to demonstrate direct vascular contiguity and tumor metabolic activity.

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