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Pulmonary Vein Tumor Invasion from Chondrosarcoma

Imaging findings

CT chest shows extensive, calcified metastatic lung masses containing chondroid matrix. There is direct, contiguous invasion of the bilateral inferior pulmonary veins and left atrium by the tumor, mimicking large-vessel venous thrombosis.

Key takeaways

Primary bone tumors like chondrosarcoma or osteosarcoma can produce calcified or ossified lung metastases. These aggressive lesions can invade local vascular structures, particularly the pulmonary veins, leading to tumor thrombus extension into the left atrium. This must be distinguished from thromboembolic disease as it carries a high risk of systemic embolization.

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