Allergic Bronchopulmonary Aspergillosis (ABPA) with Chronic Eosinophilic Pneumonia
Imaging findings
CT demonstrates central bronchiectasis with high-attenuation (mucoid) impaction of the bronchi in a distribution consistent with allergic bronchopulmonary aspergillosis (ABPA), together with coexistent peripheral consolidative opacities in a pattern resembling organizing pneumonia, biopsy-proven as chronic eosinophilic pneumonia (CEP). The patient has underlying asthma.
Key takeaways
ABPA and chronic eosinophilic pneumonia (CEP) are both allergic/eosinophilic lung disorders that can coexist, as both conditions share an underlying hypersensitivity mechanism. ABPA is characterized by high-attenuation central mucoid impaction and central bronchiectasis, while CEP presents with peripheral consolidation and ground-glass opacity. Their concurrent presence in an asthmatic patient is rare but biologically plausible.
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