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Post-Intubation Tracheal Stenosis in the Setting of Stevens-Johnson Syndrome

Imaging findings

CT in a young patient with a history of Stevens-Johnson syndrome and prolonged intubation demonstrates segmental subglottic tracheal narrowing near the thoracic inlet on both axial and coronal reformats, with circumferential wall thickening and luminal compromise.

Key takeaways

Post-intubation tracheal stenosis typically results from ischemic mucosal injury at the endotracheal cuff site or subglottically, but it can be markedly exacerbated by pre-existing or concurrent mucosal injury such as Steven-Johnson syndrome (a severe mucocutaneous drug reaction). The combination of mucosal fragility and intubation injury dramatically increases the risk and severity of stenosis, even after short periods of intubation.

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