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FDG-Avid Talc Pleurodesis Mimicking Pleural Metastases

FDG-Avid Talc Pleurodesis Mimicking Pleural Metastases▶ Watch on YouTube — age-restricted, cannot embed here

Imaging findings

CT demonstrated pleural thickening and high attenuation areas along the pleural surface, characteristic of talc pleurodesis. A subsequent PET scan revealed FDG avidity in these same pleural regions.

Key takeaways

Talc pleurodesis can cause chronic inflammation that results in FDG avidity on PET scans, which can persist for years and even increase over time. This phenomenon can mimic pleural metastases, making awareness crucial for accurate interpretation and to avoid misdiagnosis, especially in patients with a history of malignancy.

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