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Pulmonary Amyloidosis in Sjögren Syndrome

Pulmonary Amyloidosis in Sjögren Syndrome▶ Watch on YouTube — age-restricted, cannot embed here

Imaging findings

Chest CT revealed multiple lung nodules and cysts, some containing calcification, a pattern highly typical of pulmonary amyloidosis. A subsequent needle biopsy confirmed the presence of amyloid deposition.

Key takeaways

The combination of multiple lung nodules and cysts, particularly with calcification, is very suggestive of pulmonary amyloidosis. These findings can be so characteristic that a biopsy might be unnecessary if the clinical context (e.g., known Sjögren syndrome) is available. Pulmonary amyloidosis is often associated with Sjögren syndrome.

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