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Angioinvasive pulmonary mucormycosis (Rhizopus)

Imaging findings

CT scan of a patient with AML and profound neutropenia shows a large right lung mass with peripheral consolidation (halo and reverse halo signs) and lack of contrast enhancement due to extensive vascular invasion and pulmonary infarction.

Key takeaways

Pulmonary mucormycosis is a highly aggressive angioinvasive infection in neutropenic patients. The presence of reverse halo signs and unenhancing pulmonary infarction on contrast CT is strongly suggestive of angioinvasion.

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