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Intravascular Fat in the Pulmonary Artery (Intravascular Lipoma)

Imaging findings

Chest CT reveals underlying emphysema and a well-defined, tubular fat-attenuating structure measuring between -60 and -80 Hounsfield units within the right pulmonary artery. This structure extends from the right main pulmonary artery into the lateral segment branch of the right middle lobe, and remains completely unchanged on serial imaging separated by one month.

Key takeaways

Finding fat within the pulmonary arteries is highly unusual and must be differentiated from a typical acute thromboembolism to prevent unnecessary, potentially harmful anticoagulation. Differentials for fat-density pulmonary arterial filling defects include intravascular lipoma, macroscopic fat emboli (which are typically more globular), embolized renal angiomyolipoma, or a chronic fibrin sheath surrounding a prior indwelling catheter.

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