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Scedosporium Apiospermum Infection in Neutropenic AML

Imaging findings

CT in a neutropenic acute myeloid leukemia (AML) patient shows an ill-defined right lower lobe mass with a ground-glass halo, which progressed over three weeks to demonstrate cavitation and internal debris, confirmed as Scedosporium apiospermum.

Key takeaways

Scedosporium apiospermum (Pseudallescheria boydii) is an opportunistic mold that clinically and radiologically mimics angioinvasive aspergillosis or mucormycosis. It is highly resistant to many standard anti-fungals, making microbiological identification critical.

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