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Ventricular Septal Rupture

Imaging findings

Cardiac CT obtained one week after a myocardial infarction demonstrates a large defect in the apical interventricular septum (ischemic VSD) with an associated rupture of the right ventricular free wall apex, resulting in contrast-opacified blood entering the adjacent pericardial/rupture space.

Key takeaways

Ventricular septal rupture (VSR) and free wall rupture are rare, catastrophic mechanical complications of acute myocardial infarction, typically occurring 3-7 days post-infarction during the phase of coagulation necrosis. VSR leads to a high-velocity left-to-right shunt and rapid clinical deterioration, requiring urgent surgical or percutaneous closure.

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