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Parathyroid Adenoma

Imaging findings

Chest CT in a patient with hypercalcemia shows an incidental, highly vascular, and intensely enhancing nodule situated posterior to the right thyroid lobe, which appears diffusely hypo-attenuating on non-contrast CT. Tc-99m sestamibi scan confirms intense, focal tracer retention within the nodule.

Key takeaways

Parathyroid adenomas are benign endocrine neoplasms that are the most common cause of primary hyperparathyroidism. On CT, they are hypervascular and can easily be overlooked or misidentified as thyroid tissue on contrast-enhanced scans. Evaluating non-contrast attenuation (where they are hypo-attenuating compared to thyroid) and verifying with Tc-99m sestamibi scintigraphy is diagnostic.

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