Alveolar Septal Amyloidosis (TTR type)
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Imaging findings
Parenchymal findings consisted of linear opacities, which had an appearance that was almost vascular or branched centrilobular, accompanied by ground-glass opacity.
Key takeaways
This case demonstrates the rare imaging manifestation of alveolar septal amyloidosis, specifically the TTR (transthyretin) type, in a patient who underwent heart transplantation for amyloidosis. While typically presenting as well-defined centrilobular lines, sometimes with calcification, this case showed a more linear and branchy pattern with ground glass, confirmed by biopsy. The pulmonary involvement can be indolent even post-transplant.
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See all cases from September 24, 2015 →