CTICasesAnti-Synthetase Syndrome (Anti-Jo-1) with Organizing Pneumonia
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Imaging findings
Multiple bilateral patchy, multifocal, multi-lobar opacities, initially most extensive in the lower lung zones in 2009. A follow-up in 2015 showed a similar pattern of patchy focal consolidated opacities in both lungs, although with a somewhat different distribution and less prominence in the lower lung zones.
Key takeaways
This case illustrates the characteristic and persistent radiographic findings of organizing pneumonia in a patient with anti-synthetase syndrome (anti-Jo-1 positive). The diagnosis was confirmed by lung biopsy showing organizing pneumonia and lymphocytes. The patient's condition fluctuates with immunosuppression, demonstrating the chronic and relapsing nature of lung involvement in this autoimmune disorder. As an interstitial pneumonia, this falls under ILD.
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