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Bleomycin-Induced Lung Toxicity

Imaging findings

CT chest shows bilateral, nodular ground-glass opacities and peri-lobular consolidation in an organizing pneumonia pattern. The patient is a young male with testicular carcinoma post-bleomycin chemotherapy, and was minimally symptomatic.

Key takeaways

Bleomycin-induced pulmonary toxicity affects about 15% of patients treated for testicular cancer. It typically presents with an organizing pneumonia pattern, which can progress to permanent fibrosis. Clinicians must monitor pulmonary function tests and recognize these early CT signs.

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