CTICasesDendriform Pulmonary Ossification in UIP
Imaging findings
Serial CT chest scans over three years show progressive, branching, calcified/ossified interstitial structures (dendriform pulmonary ossification) in a peripheral, subpleural distribution, arising within a background of worsening pulmonary fibrosis.
Key takeaways
Dendriform pulmonary ossification (DPO) is a form of metaplastic bone formation in the lung interstitium. It is highly associated with fibrotic interstitial lung diseases, particularly the usual interstitial pneumonia (UIP) pattern, and its progression correlates with worsening fibrosis.
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