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Macklin Phenomenon

Imaging findings

CT of a patient with severe asthma shows pneumomediastinum and air dissecting along the bronchovascular sheath (subpleural interstitial emphysema/edema), consistent with the Macklin phenomenon. A small pneumothorax is also present.

Key takeaways

The Macklin phenomenon is a common cause of pneumomediastinum in patients with asthma or trauma. It involves alveolar rupture, dissection of air into the bronchovascular interstitium, and subsequent tracking of gas into the mediastinum.

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