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Good Syndrome

Imaging findings

CT shows a large, lobulated anterior mediastinal mass (thymoma) associated with diffuse infectious bronchiolitis, tree-in-bud opacities, and bronchiectasis in the lower lobes. Flow cytometry confirmed hypogammaglobulinemia.

Key takeaways

Good syndrome is a rare paraneoplastic immunodeficiency characterized by thymoma and hypogammaglobulinemia. It leads to recurrent, severe sinopulmonary infections, bronchiolitis, and bronchiectasis.

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