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Pulmonary Langerhans Cell Histiocytosis

Imaging findings

Chest CT shows multiple bizarrely shaped, cavitating nodules and cysts lining the airways in the upper and middle lung zones. The patient has no history of tobacco use but is a heavy daily marijuana smoker.

Key takeaways

Pulmonary Langerhans cell histiocytosis (PLCH) is a smoking-related interstitial lung disease. While strongly associated with cigarette smoking, it can also develop in individuals who exclusively and heavily inhale marijuana smoke.

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