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Thesaurisosis (Hairspray-Induced Lung Disease)

Imaging findings

Chest radiograph shows hyperinflated lungs. High-resolution chest CT shows diffuse bronchial wall thickening and mucus impaction in the segmental and subsegmental bronchi without bronchiectasis, but no significant mosaic perfusion. Open lung biopsy confirms follicular bronchiolitis, goblet cell metaplasia, mucostasis, and non-necrotizing granulomas in a hair stylist with 23 years of exposure.

Key takeaways

Thesaurisosis is an obsolete or rare term describing a foreign-body granulomatous lung reaction to inhaled cosmetic hairsprays. It typically manifests with cough, dyspnea, and airways disease. Histopathology can show follicular bronchiolitis and sarcoid-like granulomas, which can mimic hypersensitivity pneumonitis or sarcoidosis. Symptoms typically improve upon cessation of exposure and steroid therapy.

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