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Cavitary Pulmonary Metastases from Bladder Cancer

Imaging findings

Serial chest CT scans in a patient with history of transitional cell carcinoma of the bladder demonstrate multiple pulmonary nodules, several of which develop progressive cavitation with very thin walls and internal fluid levels. Surrounding ground-glass opacity is present, representing focal hemorrhage.

Key takeaways

Transitional cell carcinomas of the bladder are epithelial malignancies that can metastasize to the lungs. Similar to other squamous-cell-like carcinomas, they have a tendency to undergo central necrosis and cavitation, which can produce characteristic thin-walled cavitary metastases. Chemotherapy can sometimes precipitate or accelerate this cavitary transformation.

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