CTICasesProgression of hypersensitivity pneumonitis to chronic fibrosis
Imaging findings
Serial CT scans over 8 years in an agricultural worker show progression from an acute cellular HP pattern (centrilobular nodules and air trapping) to severe, chronic fibrotic HP with peribronchial/peripheral fibrosis.
Key takeaways
Incomplete antigen avoidance in patients with subacute HP can lead to progressive, irreversible pulmonary fibrosis. Serial imaging demonstrates the transition from ground-glass nodularity to chronic fibrotic remodeling.
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