CTICasesRadiation Recall Pneumonitis
Imaging findings
CT chest shows new, focal areas of consolidation and ground-glass opacity localized precisely within a prior radiation port in the right lung, developing several weeks after the initiation of a new chemotherapy regimen. A prior CT from a year earlier showed only mature, stable radiation scarring in the same region.
Key takeaways
Radiation recall pneumonitis is an inflammatory lung reaction that occurs in previously irradiated lung tissue triggered by the subsequent administration of systemic chemotherapeutic or immunotherapeutic agents. It represents a drug-induced reactivation of latent radiation damage. It occurs within the boundaries of the prior radiation field and typically responds well to corticosteroids.
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