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Legionnaires' Disease and COVID-19 Co-infection

Imaging findings

CT chest shows dense, consolidative airspace opacities in the lower lobes (characteristic of Legionella) with surrounding peripheral ground-glass opacities (characteristic of COVID-19). Dual PCR testing was positive for both pathogens.

Key takeaways

Co-infection with multiple respiratory pathogens (e.g., Legionella pneumophila and SARS-CoV-2) can produce a hybrid imaging pattern on CT, combining dense, lobar bacterial consolidation with viral peripheral ground glass. Prompt microbiological identification is required to guide targeted therapy.

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